Azasetron hydrochloride ( Azasetron hydrochloride;Y 25130; Y-25130; Y25130. )

Catalog No. M10908 CAS No. 123040-16-4

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Product Name

Azasetron hydrochloride
Note

Research use only, not for human use.
Brief Description

Azasetron Hydrochloride is a 5-HT3 receptor antagonist which is used as an anti-emetic.
Description

Azasetron Hydrochloride is a 5-HT3 receptor antagonist which is used as an anti-emetic.Azasetron inhibited the specific binding of [3H]quipazine to 5-HT3 receptors at the synaptic membranes of the rat cerebral cortex.
Synonyms

Azasetron hydrochloride;Y 25130; Y-25130; Y25130.
Pathway

Endocrinology/Hormones
Target

5-HT Receptor
Recptor

5-HT3
Research Area

Neurological Disease
Indication

——

CAS Number

123040-16-4
Formula Weight

386.27
Molecular Formula

C17H20ClN3O3·HCl
Purity

>98%(HPLC)
Solubility

Water: 3 mg/mL (7.76 mM)
SMILES

c1(cc(C(N[C@@H]2CN3CCC2CC3)=O)c2c(c1)N(C)C(=O)CO2)Cl.Cl
Chemical Name

2H-1,4-Benzoxazine-8-carboxamide, 3,4-dihydro-N-1-azabicyclo(2.2.2)oct-3-yl-6-chloro-4-methyl-3-oxo-, monohydrochloride

1.Katayama K, et al. Jpn J Pharmacol. 1997 Apr;73(4):357-60.

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