Azasetron hydrochloride

CAS No. 123040-16-4

Azasetron hydrochloride( Azasetron hydrochloride | Y 25130 | Y-25130 | Y25130. )

Catalog No. M10908 CAS No. 123040-16-4

Azasetron Hydrochloride is a 5-HT3 receptor antagonist which is used as an anti-emetic.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 31 In Stock
10MG 48 In Stock
25MG 86 In Stock
50MG 157 In Stock
100MG 266 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Azasetron hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Azasetron Hydrochloride is a 5-HT3 receptor antagonist which is used as an anti-emetic.
  • Description
    Azasetron Hydrochloride is a 5-HT3 receptor antagonist which is used as an anti-emetic.Azasetron inhibited the specific binding of [3H]quipazine to 5-HT3 receptors at the synaptic membranes of the rat cerebral cortex.(In Vivo):Azasetron could effectively penetrate through the skin and pass into the systemic circulation.
  • In Vitro
    ——
  • In Vivo
    Azasetron could effectively penetrate through the skin and pass into the systemic circulation. Animal Model:Four male Bama miniature pigs weighing 9-11 kg (15-16 weeks old).Dosage:0.5 mg/kg.Administration:I.V. administration via the abdominal vein.Result:The mean plasma concentration dropped to minimum at 36 h. Cmax = 44.88 ± 7.16 ng/mL) was achieved at the time point of 66.00 ± 22.98 h (Tmax).
  • Synonyms
    Azasetron hydrochloride | Y 25130 | Y-25130 | Y25130.
  • Pathway
    Endocrinology/Hormones
  • Target
    5-HT Receptor
  • Recptor
    5-HT3
  • Research Area
    Neurological Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    123040-16-4
  • Formula Weight
    386.27
  • Molecular Formula
    C17H20ClN3O3·HCl
  • Purity
    >98% (HPLC)
  • Solubility
    Water: 3 mg/mL (7.76 mM)
  • SMILES
    c1(cc(C(N[C@@H]2CN3CCC2CC3)=O)c2c(c1)N(C)C(=O)CO2)Cl.Cl
  • Chemical Name
    2H-1,4-Benzoxazine-8-carboxamide, 3,4-dihydro-N-1-azabicyclo(2.2.2)oct-3-yl-6-chloro-4-methyl-3-oxo-, monohydrochloride

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Katayama K, et al. Jpn J Pharmacol. 1997 Apr;73(4):357-60.
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